Bone mineral density and nutritional status in children with chronic inflammatory bowel disease

Background—Osteoporosis has been reported in adult patients with inflammatory bowel disease. Aims—To evaluate bone mineral density (BMD), nutritional status, and determinants of BMD in children with inflammatory bowel disease. Patients—Fifty five patients (34 boys and 21 girls, age range 4–18) were...

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Bibliographic Details
Published in:Gut 1998-02, Vol.42 (2), p.188-194
Main Authors: Boot, A M, Bouquet, J, Krenning, E P, de Muinck Keizer-Schrama, S M P F
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Adolescent
Androgens
Biological and medical sciences
Body Composition
Body Height
Body Mass Index
Bone Density
bone mineral density
Child
Child, Preschool
children
Colitis, Ulcerative - metabolism
Colitis, Ulcerative - physiopathology
corticosteroid treatment
Crohn Disease - drug therapy
Crohn Disease - metabolism
Crohn Disease - physiopathology
Cross-Sectional Studies
Electric Impedance
Female
Gastroenterology. Liver. Pancreas. Abdomen
Glucocorticoids - adverse effects
Humans
Inflammatory Bowel Disease
Longitudinal Studies
Male
Medical sciences
Nutritional Status
Other diseases. Semiology
Prednisolone - adverse effects
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Studies
Vitamin D
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Summary:Background—Osteoporosis has been reported in adult patients with inflammatory bowel disease. Aims—To evaluate bone mineral density (BMD), nutritional status, and determinants of BMD in children with inflammatory bowel disease. Patients—Fifty five patients (34 boys and 21 girls, age range 4–18) were studied; 22 had Crohn’s disease and 33 ulcerative colitis. Methods—Lumbar spine and total body BMD, and body composition were assessed by dual energy x ray absorptiometry (DXA). Results were expressed as standard deviation scores (SDS). Lean body mass was also assessed by bioelectrical impedance analysis (BIA). Yearly measurements during two years were performed in 21 patients. Results—The mean SDS of lumbar spine BMD and total body BMD were significantly lower than normal (−0.75 and −0.95, both p
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.42.2.188