Once daily ceftriaxone and gentamicin for the treatment of febrile neutropenia

AIMS To evaluate the pharmacokinetics of once daily (OD) gentamicin and its effectiveness as part of an OD regimen for the empirical treatment of febrile neutropenia in children with cancer. SUBJECTS 59 children aged 6 months to 16 years (mean (SD) 5.7 (4) years) with febrile neutropenia (neutrophil...

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Bibliographic Details
Published in:Archives of disease in childhood 1999-02, Vol.80 (2), p.125-131
Main Authors: Tomlinson, Richard J, Ronghe, Milind, Goodbourne, Colin, Price, Christine, Lilleyman, John S, Das, Satya, Saha, Vaskar
Format: Article
Language:English
Subjects:
Adolescent
Antibiotics
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
cancer
ceftriaxone
Ceftriaxone - administration & dosage
Ceftriaxone - therapeutic use
Child
Child, Preschool
Drug Administration Schedule
Drug dosages
Drug Therapy, Combination - administration & dosage
Drug Therapy, Combination - therapeutic use
febrile neutropenia
Female
Fever - drug therapy
Fever - etiology
gentamicin
Gentamicins - administration & dosage
Gentamicins - therapeutic use
Humans
Infant
Infections
Male
Medical sciences
Meta Analysis
Neoplasms - complications
Neutropenia
Neutropenia - drug therapy
Neutropenia - etiology
once daily treatment
Organisms
Original
Patients
Pharmacology. Drug treatments
Prospective Studies
Studies
Toxicity
Citations: Items that cite this one
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Summary:AIMS To evaluate the pharmacokinetics of once daily (OD) gentamicin and its effectiveness as part of an OD regimen for the empirical treatment of febrile neutropenia in children with cancer. SUBJECTS 59 children aged 6 months to 16 years (mean (SD) 5.7 (4) years) with febrile neutropenia (neutrophil count
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.80.2.125