Goodpasture's syndrome: treatment with plasmapheresis, immunosuppression, and anticoagulation

We report 3 children with Goodpasture's syndrome. In 2 children the diagnosis was delayed, treatment began late, and they did not recover renal function. In the third child early diagnosis and intensive treatment with plasmapheresis, immunosuppression, and anticoagulation resulted in an initial...

Full description

Saved in:

Bibliographic Details
Published in:	Archives of disease in childhood 1983-09, Vol.58 (9), p.697-702
Main Authors:	Levin, M, Rigden, S P, Pincott, J R, Lockwood, C M, Barratt, T M, Dillon, M J
Format:	Article
Language:	eng
Subjects:	Anti-Glomerular Basement Membrane Disease - immunology Anti-Glomerular Basement Membrane Disease - therapy Antibodies - analysis Anticoagulants - therapeutic use Basement Membrane - immunology Biological and medical sciences Child Child, Preschool Combined Modality Therapy Female Glomerulonephritis Humans Immunosuppression Kidney Glomerulus - immunology Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Plasmapheresis
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	We report 3 children with Goodpasture's syndrome. In 2 children the diagnosis was delayed, treatment began late, and they did not recover renal function. In the third child early diagnosis and intensive treatment with plasmapheresis, immunosuppression, and anticoagulation resulted in an initial return of renal function after a prolonged period of anuria. In this child, however, although there was no evidence of disease activity, further deterioration of renal function subsequently occurred.
ISSN:	0003-9888 1468-2044