TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein

The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments. The TTG1 locus has been isolated by positional cloning, and...

Full description

Saved in:
Bibliographic Details
Published in:The Plant cell 1999-07, Vol.11 (7), p.1337-1349
Main Authors: Walker, A.R, Davison, P.A, Bolognesi-Winfield, A.C, James, C.M, Srinivasan, N, Blundell, T.L, Esch, J.J, Marks, M.D, Gray, J.C
Format: Article
Language:English
Subjects:
Alleles
Amino Acid Sequence
amino acid sequences
Amino acids
anthocyanins
Anthocyanins - biosynthesis
Arabidopsis - genetics
Arabidopsis - metabolism
Arabidopsis Proteins
Arabidopsis thaliana
Base Sequence
biosynthesis
buds
cell differentiation
chromosome mapping
DNA
DNA, Plant
flowers
genbank/aj133743
gene expression
Genes
genetic complementation
Genetic Complementation Test
Genetic loci
Genetic mutation
Genomics
leaves
loci
meristems
messenger RNA
Molecular Sequence Data
Mutation
nucleotide sequences
plant proteins
Plant Proteins - genetics
Plant Proteins - physiology
Plants
Protein Conformation
Proteins
restriction mapping
RNA
roots
Sequence Homology, Amino Acid
stems
Trichomes
ttg1 locus
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments. The TTG1 locus has been isolated by positional cloning, and its identity was confirmed by complementation of a ttg1 mutant. The locus encodes a protein of 341 amino acid residues with four WD40 repeats. The protein is similar to AN11, a regulator of anthocyanin biosynthesis in petunia, and more distantly related to those of the beta subunits of heterotrimeric G proteins, which suggests a role for TTG1 in signal transduction to down-stream transcription factors. The 1.5-kb TTG1 transcript is present in all major organs of Arabidopsis. Sequence analysis of six mutant alleles has identified base changes producing truncations or single amino acid changes in the TTG1 protein.
ISSN:1040-4651
1532-298X
DOI:10.1105/tpc.11.7.1337