Effects of storage on activity and subunit structure of rabbit skeletal-muscle AMP deaminase

On storage, AMP deaminase is converted into a form exhibiting hyperbolic kinetics even at low KCl concentration. This effect results from cleavage of the enzyme subunit (mol.wt. 79 000) to a product of similar size to the component of approx. mol.wt. 70 000 present in trace amounts in AMP deaminase...

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Bibliographic Details
Published in:Biochemical journal 1980-08, Vol.189 (2), p.367-368
Main Authors: Ranieri-Raggi, M, Raggi, A
Format: Article
Language:English
Subjects:
AMP Deaminase - metabolism
Animals
Chemical Phenomena
Chemistry
Drug Storage
Kinetics
Muscles - enzymology
Nucleotide Deaminases - metabolism
Potassium Chloride
Rabbits
Time Factors
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Description
Summary:On storage, AMP deaminase is converted into a form exhibiting hyperbolic kinetics even at low KCl concentration. This effect results from cleavage of the enzyme subunit (mol.wt. 79 000) to a product of similar size to the component of approx. mol.wt. 70 000 present in trace amounts in AMP deaminase just prepared from fresh muscle.
ISSN:0264-6021
1470-8728
DOI:10.1042/bj1890367