Efficacy of antihypertensive treatment for target organ protection in patients with masked hypertension (ANTI-MASK): a multicentre, double-blind, placebo-controlled trial

Masked hypertension is associated with target organ damage (TOD) and adverse health outcomes, but whether antihypertensive treatment improves TOD in patients with masked hypertension is unproven. In this multicentre, randomised, double-blind, placebo-controlled trial at 15 Chinese hospitals, untreat...

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Bibliographic Details
Published in:EClinicalMedicine 2024-08, Vol.74, p.102736, Article 102736
Main Authors: Huang, Jian-Feng, Zhang, Dong-Yan, An, De-Wei, Li, Ming-Xuan, Liu, Chang-Yuan, Feng, Ying-Qing, Zheng, Qi-Dong, Chen, Xin, Staessen, Jan A., Wang, Ji-Guang, Li, Yan, Zhang, Yi-Qing, Chang, Gui-Li, Hu, Zhe, Li, Xi-Da, Liu, Can, Huang, Jia-Yi, Yu, Yu-Ling, Wang, Yi-Yun, Zhang, Xue-Ning, Yu, Jing, Ma, Rui-Xin, Liu, Heng-Xia, Chen, Xiao-Ping, Meng, Qing-Tao, Zhang, Zhi-Peng, Dou, Yu, Zhu, Mei-Yu, Wang, Wen-Juan, Zhu, Li-Li, Zhang, Min, Jiang, Yi-Nong, Lu, Yan, Yu, Wei, Xu, Xiao-Ling, Dai, Qiu-Yan, Zhu, Yu-Feng, Zhang, Hui-Jie, Zhang, Yu, Zhang, Jin-Shun, Bu, Pei-Li, Liu, Ling-Xin, Mu, Jian-Jun, Xu, Jing-Tao, Liao, Yue-Yuan, Guo, Hao, Liang, Xin-Yue
Format: Article
Language:English
Subjects:
Ambulatory blood pressure monitoring
Antihypertensive treatment
Masked hypertension
Randomised clinical trial
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Summary:Masked hypertension is associated with target organ damage (TOD) and adverse health outcomes, but whether antihypertensive treatment improves TOD in patients with masked hypertension is unproven. In this multicentre, randomised, double-blind, placebo-controlled trial at 15 Chinese hospitals, untreated outpatients aged 30–70 years with an office blood pressure (BP) of
ISSN:2589-5370
2589-5370
DOI:10.1016/j.eclinm.2024.102736