Fatigue

Diagnostic criteria for chronic fatigue syndrome Inclusion criteria Clinically evaluated, medically unexplained fatigue of at least 6 months' duration that is Of new onset (not life long) Not result of ongoing exertion Not substantially alleviated by rest Associated with a substantial reduction...

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Bibliographic Details
Published in:	BMJ 2002-08, Vol.325 (7362), p.480-483
Main Authors:	Sharpe, Michael, Wilks, David
Format:	Article
Language:	eng
Subjects:	Antidepressants Anxiety - etiology Art galleries & museums Attitude to Health Chronic Disease Chronic fatigue syndrome Clinical Review Cognition & reasoning Cognitive Behavioral Therapy - methods Complaints Depression - etiology Exercise Therapy - methods Fatigue - diagnosis Fatigue - etiology Fatigue - therapy Humans Immunology Mental depression Muscle pain Occupational Diseases - etiology Occupational Diseases - therapy Patient Education as Topic Physiology Psychosis Quality of life Stress, Psychological - etiology Stress, Psychological - therapy Therapy Thyroid gland Urine
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Summary:	Diagnostic criteria for chronic fatigue syndrome Inclusion criteria Clinically evaluated, medically unexplained fatigue of at least 6 months' duration that is Of new onset (not life long) Not result of ongoing exertion Not substantially alleviated by rest Associated with a substantial reduction in previous level of activities Occurrence of 4 or more of the following symptoms Subjective memory impairment, sore throat, tender lymph nodes, muscle pain, joint pain, headache, unrefreshing sleep, post-exertional malaise lasting more than 24 hours Exclusion criteria Active, unresolved, or suspected medical disease or psychotic, melancholic, or bipolar depression (but not uncomplicated majordepression), psychotic disorders, dementia, anorexia or bulimia nervosa, alcohol or other substance misuse, severe obesity The term myalgic encephalomyelitis (or encephalopathy) has been used in Britain and elsewhere to describe a poorly understood illness in which a prominent symptom is chronic fatigue exacerbated by activity. The history should also cover Screening tests for fatigue Full blood count Erythrocyte sedimentation rate or C reactive protein Liver function tests Urea and electrolytes Thyroid stimulating hormone and thyroid function tests Creatine kinase Urine and blood tests for glucose Urine test for protein Systematic inquiry for diseases often associated with fatigue Symptoms of depression anxiety and sleep disorder Patients' own understanding of their illness and how they cope with it Current social stresses.
ISSN:	0959-8138 1468-5833 1756-1833