Congenital anomalies of the kidney and urinary tract: antenatal diagnosis, management and counselling of families

Congenital anomalies of the kidney and urinary tract are collectively one of the most commonly diagnosed antenatal conditions. Clinicians have several tools available to diagnose anomalies, including imaging, biomarkers, family history and genetic studies. In certain cases, antenatal interventions s...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2024-04, Vol.39 (4), p.1065-1075
Main Authors: Walker, Emma Y. X., Winyard, Paul, Marlais, Matko
Format: Article
Language:English
Subjects:
Amniotic fluid
Antibiotics
Biomarkers
Births
Bladder
Congenital defects
Congenital diseases
Counseling
Educational Review
Embryology
Families & family life
Family medical history
Female
Humans
Hydronephrosis
Kidney - abnormalities
Kidney - diagnostic imaging
Kidney diseases
Kidneys
Medicine
Medicine & Public Health
Morbidity
Multidisciplinary teams
Nephrology
Parents & parenting
Pediatrics
Pregnancy
Prenatal care
Prenatal Diagnosis
Ultrasonic imaging
Urinary tract
Urinary Tract - abnormalities
Urinary Tract - diagnostic imaging
Urinary tract infections
Urogenital Abnormalities - diagnostic imaging
Urogenital Abnormalities - therapy
Urogenital system
Urology
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Description
Summary:Congenital anomalies of the kidney and urinary tract are collectively one of the most commonly diagnosed antenatal conditions. Clinicians have several tools available to diagnose anomalies, including imaging, biomarkers, family history and genetic studies. In certain cases, antenatal interventions such as vesico-amniotic shunting may be considered to improve postnatal outcomes. Congenital kidney anomalies detected antenatally can vary in clinical significance from almost no impact postnatally to significant morbidity and perinatal mortality. Prognosis broadly depends on kidney size, structure and amount of amniotic fluid, alongside genetics and family history, and progression on subsequent scans. It is important to counsel parents appropriately using a parent-focused and personalised approach. The use of a multidisciplinary team should always be considered.
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-023-06137-z