Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: a systematic review of propensity score-matched studies

Outcomes of laparoscopic liver resection (LLR) versus open LR (OLR) for intrahepatic cholangiocarcinoma (ICCA) are heterogeneous. We aimed to compare LLR and OLR for ICCA based on propensity-score-matched (PSM) studies. Two reviewers independently searched the online databases (PubMed, Embase, and C...

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Bibliographic Details
Published in:Updates in surgery 2023-12, Vol.75 (8), p.2049-2061
Main Authors: Hu, Ya-Fei, Hu, Hai-Jie, Ma, Wen-Jie, Jin, Yan-Wen, Li, Fu-Yu
Format: Article
Language:English
Subjects:
Bile Duct Neoplasms - surgery
Bile Ducts, Intrahepatic
Carcinoma, Hepatocellular - surgery
Cholangiocarcinoma - surgery
Hepatectomy - adverse effects
Humans
Laparoscopy - adverse effects
Length of Stay
Liver Neoplasms - surgery
Medicine
Medicine & Public Health
Postoperative Complications - etiology
Propensity Score
Retrospective Studies
Review
Review Article
Surgery
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Summary:Outcomes of laparoscopic liver resection (LLR) versus open LR (OLR) for intrahepatic cholangiocarcinoma (ICCA) are heterogeneous. We aimed to compare LLR and OLR for ICCA based on propensity-score-matched (PSM) studies. Two reviewers independently searched the online databases (PubMed, Embase, and Cochrane Library) for PSM studies that compared LLR and OLR for ICCA. The Ottawa–Newcastle Quality Assessment Scale with a cutoff of ≥ 7 was used to define higher-quality literature. Only ‘high-quality’ PSM analyses of the English language that met all our inclusion criteria were considered. A total of ten PSM trials were included in the analyses. Compared with OLR, although the lymph node dissection (LND) (RR = 0.67) and major hepatectomy rates were lower in the LLR group (RR = 0.87), higher R0 resections (RR = 1.05) and lower major complications (Clavien–Dindo grade ≥ III) (RR = 0.72) were also observed in the LLR group. In addition, patients in the LLR group showed less estimated blood loss (MD = − 185.52 ml) and shorter hospital stays as well (MD = − 2.75 days). Further analysis found the overall survival (OS) (HR = 0.91), disease-free survival (DFS) (HR = 0.95), and recurrence-free survival (HR = 0.80) for patients with ICCA after LLR were all comparable to those of OLR. LLR for selected ICCA patients may be technically safe and feasible, providing short-term benefits and achieving oncological efficacy without compromising the long-term survival of the patients.
ISSN:2038-131X
2038-3312
DOI:10.1007/s13304-023-01648-8