Preconception Periodontitis and Risk of Spontaneous Abortion in a Prospective Cohort Study

Abstract Few studies have evaluated the association between periodontitis and spontaneous abortion (SAB), and all had limitations. We used data from the Pregnancy Study Online (PRESTO), a prospective preconception cohort study of 3,444 pregnancy planners in the United States and Canada (2019–2022),...

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Bibliographic Details
Published in:American journal of epidemiology 2023-09, Vol.192 (9), p.1509-1521
Main Authors: Bond, Julia C, Wise, Lauren A, Fox, Matthew P, Garcia, Raul I, Murray, Eleanor J, White, Katharine O, Rothman, Kenneth J, Hatch, Elizabeth E, Heaton, Brenda
Format: Article
Language:English
Subjects:
Bias
Cohort analysis
Confidence intervals
Diagnosis
Gestation
Gum disease
Miscarriage
Original Contribution
Periodontitis
Pregnancy
Questionnaires
Regression analysis
Regression models
Statistical analysis
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Summary:Abstract Few studies have evaluated the association between periodontitis and spontaneous abortion (SAB), and all had limitations. We used data from the Pregnancy Study Online (PRESTO), a prospective preconception cohort study of 3,444 pregnancy planners in the United States and Canada (2019–2022), to address this question. Participants provided self-reported data on periodontitis diagnosis, treatment, and symptoms of severity (i.e., loose teeth) via the enrollment questionnaire. SAB (pregnancy loss at
ISSN:0002-9262
1476-6256
1476-6256
DOI:10.1093/aje/kwad142