Patient Perception of Skin Cancer Reduction by Nicotinamide Correlates With Use

IntroductionNicotinamide (Vitamin B3) has been shown to reduce the rate of non-melanoma skin cancers by 23%, yet most patients do not know that this supplement reduces skin cancer. Understanding patient beliefs about skin cancer reduction attributed to nicotinamide is important to appropriately coun...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-08, Vol.15 (8), p.e44403-e44403
Main Authors: Schneider, Justine G, Majidian, Mandy, Moy, Ronald L
Format: Article
Language:English
Subjects:
Dermatology
Disease prevention
DNA damage
DNA repair
Melanoma
Mortality
Patients
Perceptions
Preventive Medicine
Skin cancer
Squamous cell carcinoma
Sunscreen
Surgery
Vitamin deficiency
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Summary:IntroductionNicotinamide (Vitamin B3) has been shown to reduce the rate of non-melanoma skin cancers by 23%, yet most patients do not know that this supplement reduces skin cancer. Understanding patient beliefs about skin cancer reduction attributed to nicotinamide is important to appropriately counsel patients on oral supplement use and ultimately to prevent non-melanoma skin cancers.ObjectiveThe objective of this study was to determine the association between nicotinamide use and perceived efficacy in skin cancer reduction.MethodsPatients who underwent Mohs surgery in 2019 were sent an online survey assessing nicotinamide use, efficacy compared to sunscreen, and perceived skin cancer risk reduction.ResultsData from 50 surveys revealed a perceived risk reduction attributed to nicotinamide of 31.2% for basal cell carcinoma (BCC), 30.2% for squamous cell carcinoma (SCC), and 24.3% for melanoma. In the subset of respondents taking nicotinamide, the perceived risk reduction was significantly higher at 41.2% for BCC and 38.3% for SCC (p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.44403