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The irrational and prolonged use of antibiotics in orthopaedic infections poses a major threat to the development of antimicrobial resistance. To combat antimicrobial resistance, researchers have implemented various novel and innovative modalities to curb infections. Nanotechnology involves doping i...

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Bibliographic Details
Published in:World journal of orthopedics 2023-09, Vol.14 (9), p.682-689
Main Authors: Bondarenko, Stanislav, Filipenko, Volodymyr, Ashukina, Nataliya, Maltseva, Valentyna, Ivanov, Gennadiy, Lazarenko, Iurii, Sereda, Dmytro, Schwarzkopf, Ran
Format: Article
Language:English
Subjects:
Basic Study
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Summary:The irrational and prolonged use of antibiotics in orthopaedic infections poses a major threat to the development of antimicrobial resistance. To combat antimicrobial resistance, researchers have implemented various novel and innovative modalities to curb infections. Nanotechnology involves doping ions/metals onto the scaffolds to reach the target site to eradicate the infective foci. In this connotation, we reviewed silver nanoparticle technology in terms of mechanism of action, clinical applications, toxicity, and regulatory guidelines to treat orthopaedic infections.
ISSN:2218-5836
2218-5836
DOI:10.5312/wjo.v14.i9.682