Influence of Air Pollutants on the Disease Activity and Quality of Life in Rheumatoid Arthritis, an Iranian Observational Longitudinal Study

BackgroundEnvironmental exposures and genetic predisposition interactions may result in autoimmune rheumatic diseases. This study aimed to determine the effect of outdoor air pollutants on the activity of rheumatoid arthritis (RA) in a longitudinal follow-up. MethodsWe longitudinally studied 50 pati...

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Published in:Medical journal of the Islamic Republic of Iran 2023, Vol.37, p.65-65
Main Authors: Sahebari, Maryam, Esmailpour, Maryam, Esmaili, Habibollah, Orooji, Arezoo, Dowlatabadi, Yousef, Nabavi Mahali, Shima, Rajabi, Enayat, Salari, Masoumeh
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Language:English
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Summary:BackgroundEnvironmental exposures and genetic predisposition interactions may result in autoimmune rheumatic diseases. This study aimed to determine the effect of outdoor air pollutants on the activity of rheumatoid arthritis (RA) in a longitudinal follow-up. MethodsWe longitudinally studied 50 patients with RA bimonthly over 6 months in Mashhad, one of the most polluted cities in Iran. Disease activity and health-related quality of life (HRQoL) were examined according to the disease activity score (DAS28ESR), health assessment questionnaires (HAQ), physical health component summary (PCS), and visual analogue scale (VAS) criteria. The outdoor air pollutant was measured by monitoring the average concentration of nitrogen oxide (NO), carbon monoxide (CO), O2 level, Sulfur dioxide (SO2), and some particles less than 10 and 2.5 micrometers in diameter (PM
ISSN:1016-1430
2251-6840
DOI:10.47176/mjiri.37.65