Cost-Effectiveness of HIV Retention and Re-engagement Interventions in High-Income Countries: A Systematic Literature Review

Engagement in lifelong HIV care is critical for both patient and public health, yet there are limited resources to invest in improving HIV outcomes. We systematically reviewed evidence on the cost-effectiveness of retention and re-engagement interventions. We searched five databases for peer-reviewe...

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Bibliographic Details
Published in:AIDS and behavior 2022-07, Vol.26 (7), p.2159-2168
Main Authors: Wheatley, Margo M., Knowlton, Gregory S., Butler, Mary, Enns, Eva A.
Format: Article
Language:English
Subjects:
Attrition
Cost-Benefit Analysis
Costs
Developed Countries
Disease management
Effectiveness
Health behavior
Health Psychology
Health risks
Health services
HIV
HIV Infections - epidemiology
HIV Infections - prevention & control
Human immunodeficiency virus
Humans
Income
Industrialized nations
Infectious Diseases
Intervention
Literature reviews
Medicine
Medicine & Public Health
Patient compliance
Public Health
Quality-Adjusted Life Years
Retention
Risk groups
Substantive Review
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Summary:Engagement in lifelong HIV care is critical for both patient and public health, yet there are limited resources to invest in improving HIV outcomes. We systematically reviewed evidence on the cost-effectiveness of retention and re-engagement interventions. We searched five databases for peer-reviewed studies published between 2010 and 2020. We assessed reporting and methods quality, extracted data on target populations, interventions, and cost-effectiveness, and evaluated overall strength of evidence. Eleven studies met inclusion criteria, and eight had moderate-high quality. Cost-effectiveness estimates ranged from cost-saving to over $1,000,000/quality-adjusted life year (QALY) gained. Of the 73 cost-effectiveness ratios reported, 64% were 
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-021-03561-w