Effects of mixed oil emulsion on short-term clinical outcomes in premature infants: A prospective, multicenter, randomized controlled trial

This study compared the clinical effects of two different lipid emulsions in premature infants with gestational age  5 mg/dL (84/231 [36.4% vs. 60/234 [25.6%]), a peak value of direct bilirubin (DB) ≥ 2 mg/dL (26/231 [11.3% vs. 14/234 [6.0%]), a peak value of alkaline phosphatase (ALP) > 900 IU/L...

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Bibliographic Details
Published in:European journal of clinical nutrition 2023-08, Vol.77 (8), p.823-832
Main Authors: Yang, Qing, Kong, Juan, Bai, Rui-Miao, Yu, Wen-Ting, Zhang, Juan, Shen, Wei, Tang, Li-Xia, Zhu, Yao, Wang, Ya-Sen, Song, Si-Yu, Yang, Dong, Song, Shi-Rong, Zhang, Yi-Jia, Lin, Xin-Zhu, Wu, Fan, Li, Zhan-Kui, Mao, Jian, Tong, Xiao-Mei
Format: Article
Language:English
Subjects:
Alkaline phosphatase
Bilirubin
Birth weight
Bone diseases
Cholestasis
Clinical outcomes
Complications
Confidence intervals
Emulsions
Enteral nutrition
Enterocolitis
Fish oils
Gestational age
Growth rate
Hemorrhage
Infants
Intolerance
Lipids
Necrotizing enterocolitis
Neonates
Nutrition
Olive oil
Parenteral nutrition
Periventricular leukomalacia
Premature babies
Premature birth
Regression analysis
Retinopathy
Sepsis
Soybean oil
Soybeans
Statistical analysis
Subgroups
Triglycerides
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Summary:This study compared the clinical effects of two different lipid emulsions in premature infants with gestational age  5 mg/dL (84/231 [36.4% vs. 60/234 [25.6%]), a peak value of direct bilirubin (DB) ≥ 2 mg/dL (26/231 [11.3% vs. 14/234 [6.0%]), a peak value of alkaline phosphatase (ALP) > 900 IU/L (17/231 [7.4% vs. 7/234 [3.0%]), and a peak value of triglycerides (TG) > 3.4 mmol/L (13/231 [5.6% vs. 4/234[1.7%]]) were lower in the SMOF group (P 
ISSN:0954-3007
1476-5640
DOI:10.1038/s41430-023-01288-6