An Analysis of the Clinical and Radiological Prognostic Factors Affecting the Outcomes of Lumbar Intradiscal Biacuplasty

Intradiscal biacuplasty (IDB) has been proven to be effective for treating lumbar degenerative disc disease (DDD). However, there has not been a reported prognostic factor for IDB. The present study meticulously evaluates the general and radiographic features that may serve as markers for predicting...

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Bibliographic Details
Published in:International journal of medical sciences 2023-01, Vol.20 (8), p.1115-1122
Main Authors: Md, Meng-Yin Yang, Md, Chin-Hwee Goh, Md, Chin-Ying Wu, MSc, You-Pen Chiu, MSc, Hui-Ru Ji, Md, I-Han Hsiao, Md, Cheng-Di Chiu
Format: Article
Language:English
Subjects:
Anti-inflammatory agents
Back pain
Body mass index
Catheters
Degenerative disc disease
FDA approval
Follow-Up Studies
Humans
Intervertebral Disc Degeneration - complications
Intervertebral Disc Degeneration - diagnostic imaging
Intervertebral Disc Degeneration - therapy
Intervertebral Disc Displacement - diagnostic imaging
Intervertebral Disc Displacement - therapy
Low Back Pain - diagnostic imaging
Low Back Pain - etiology
Lumbar Vertebrae - diagnostic imaging
Lumbar Vertebrae - surgery
Magnetic resonance imaging
Nonsteroidal anti-inflammatory drugs
Patients
Prognosis
Questionnaires
Radiography
Research Paper
Surgery
Treatment Outcome
Variables
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Summary:Intradiscal biacuplasty (IDB) has been proven to be effective for treating lumbar degenerative disc disease (DDD). However, there has not been a reported prognostic factor for IDB. The present study meticulously evaluates the general and radiographic features that may serve as markers for predicting the therapeutic outcome of IDB. A prospective case series study was conducted, following time-series analysis moving averages models, with forty-one patients suffering from chronic discogenic lower back pain for more than six months. These patients subsequently received lumbar cool radiofrequency IDB and were enrolled in the study. Thirty-seven patients completed follow-up questionnaires at 1, 3, 6, and 12 months. The surgical outcomes were reported using visual analogue scale (VAS), Oswestry disability index (ODI), and the consumption of nonsteroidal anti-inflammatory drugs (NSAID). Furthermore, a univariate analysis was performed to identify prognostic factors associated with pain relief from age, gender, body mass index (BMI), and pre-operative lumbar magnetic resonance imaging reading. : Significant reductions were found in estimated VAS and ODI at the post-operative period at 1, 3, 6, and 12 months ( < 0.001). The NSAID dosage was significantly decreased at 3-month and 1-year follow-up ( < 0.05). No procedure-related complications were detected. The prognosis of IDB was not related to disc height, Pfirrmann grading or Modic endplate change. However, disc extrusions were associated with promising outcomes (VAS improvement ≥ 50%) on pain relief ( < 0.05). IDB is a good alternative choice for treating lumbar DDD. Patients with a painful extrusion lumbar disc may gain some benefits after receiving IDB following a period of failed conservative treatment. These findings may also add some references for physicians in the decision making when treating lumbar DDD.
ISSN:1449-1907
1449-1907
DOI:10.7150/ijms.85777