Impact of COVID-19 pandemic on prostate cancer outcomes at an uro-oncology referral center

ABSTRACT Introduction To evaluate the possible effects of the coronavirus disease 2019 (COVID-19) pandemic on the oncologic results of patients with prostate cancer regarding clinical staging, presence of adverse pathological outcomes, and perioperative complications. Materials and methods This retr...

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Published in:International Brazilian Journal of Urology 2023-04, Vol.49 (2), p.233-242
Main Authors: Andrade, Guilherme Miranda, Sesconetto, Lucas, Silva, Rafael Benjamim Rosa da, Santos, Gabriela Guimarães Rodrigues dos, Kayano, Paulo Priante, Baccaglini, Willy, Bezerra, Murilo Borges, Bianco, Bianca, Lemos, Gustavo Caserta, Carneiro, Arie
Format: Article
Language:English
Subjects:
COVID-19
Original
Prostatectomy
Prostatic Neoplasms
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Summary:ABSTRACT Introduction To evaluate the possible effects of the coronavirus disease 2019 (COVID-19) pandemic on the oncologic results of patients with prostate cancer regarding clinical staging, presence of adverse pathological outcomes, and perioperative complications. Materials and methods This retrospective study included patients who underwent radical prostatectomy. The time between biopsy and surgery, staging tests, final histopathological evaluation after surgery, lymphadenectomy rate, postoperative complications, and prostatic specific antigen (PSA) levels (initial and 30 days after surgery) were analyzed and compared in a group of patients before and during the pandemic period. Results We included 226 patients: 88 in the pre-pandemic period and 138 during the pandemic period. There was no statistically significant difference in mean age, body mass index, ASA, pathological locally advanced disease, the proportion of patients who underwent lymphadenectomy, and ISUP grade in the biopsy between the groups. Positive surgical margins, prostatic extracapsular extension, and PSA levels at 30 days were also similar between the groups. The mean time between medical consultation and surgery was longer in the pandemic period than in the pre-pandemic (124 vs. 107 days, p
ISSN:1677-5538
1677-6119
DOI:10.1590/s1677-5538.ibju.2022.0393