TRANSFAC: an integrated system for gene expression regulation

TRANSFAC is a database on transcription factors, their genomic binding sites and DNA-binding profiles (http://transfac.gbf.de/TRANSFAC/). Its content has been enhanced, in particular by information about training sequences used for the construction of nucleotide matrices as well as by data on plant...

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Bibliographic Details
Published in:Nucleic acids research 2000-01, Vol.28 (1), p.316-319
Main Authors: Wingender, E, Chen, X, Hehl, R, Karas, H, Liebich, I, Matys, V, Meinhardt, T, Prüss, M, Reuter, I, Schacherer, F
Format: Article
Language:English
Subjects:
Database Management Systems
Databases, Factual
Gene Expression Regulation
Internet
Transcription Factors - classification
Transcription Factors - metabolism
TRANSFAC database
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Summary:TRANSFAC is a database on transcription factors, their genomic binding sites and DNA-binding profiles (http://transfac.gbf.de/TRANSFAC/). Its content has been enhanced, in particular by information about training sequences used for the construction of nucleotide matrices as well as by data on plant sites and factors. Moreover, TRANSFAC has been extended by two new modules: PathoDB provides data on pathologically relevant mutations in regulatory regions and transcription factor genes, whereas S/MARt DB compiles features of scaffold/matrix attached regions (S/MARs) and the proteins binding to them. Additionally, the databases TRANSPATH, about signal transduction, and CYTOMER, about organs and cell types, have been extended and are increasingly integrated with the TRANSFAC data sources.
ISSN:0305-1048
1362-4962
1362-4962
DOI:10.1093/nar/28.1.316