Serum Magnesium in Patients With Acute Myocardial Infarction and Its Effect on Cardiac Complications and Mortality in Myocardial Infarction Patients

Background Magnesium is an essential micronutrient for people and is crucial in maintaining healthy cardiac function. It functions as a cofactor in a number of the body's enzyme systems, and myocardial cells are one of its target tissues. The upkeep of the myocardium's normal functional in...

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Published in:Curēus (Palo Alto, CA) CA), 2023-04, Vol.15 (4), p.e38147-e38147
Main Authors: Sabah, Zia, Wani, Javed, Deajim, Mosab, Al Zomia, Ahmed S, Asiri, Abdullah, Alqahtani, Ali A, Alansari, Wasna, Alwan, Amin, Al Qahtani, Ryan M, Raj, Berin
Format: Article
Language:English
Subjects:
Angina pectoris
Beta blockers
Cardiac arrhythmia
Cardiac/Thoracic/Vascular Surgery
Cardiology
Cardiovascular disease
Coronary vessels
Diabetes
Diuretics
Enzymes
Heart attacks
Hospitals
Internal Medicine
Kinases
Mortality
Variables
Veins & arteries
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Summary:Background Magnesium is an essential micronutrient for people and is crucial in maintaining healthy cardiac function. It functions as a cofactor in a number of the body's enzyme systems, and myocardial cells are one of its target tissues. The upkeep of the myocardium's normal functional integrity depends on a lot of things including magnesium ions. Magnesium plays an important role in the pathophysiology of cardiovascular disorders. Aim This study aims to estimate serum magnesium levels and their correlation with cardiac complications and mortality in patients with acute myocardial infarction (AMI). Methods Patients with acute myocardial infarction who visited the Prince Faisal Bin Khalid Cardiac Center within 12 hours of the onset of symptoms were the subjects of this study. On the first and fifth days following admission, the level of serum magnesium was assessed. Statistical Package for Social Sciences (SPSS) version 20 (IBM SPSS Statistics, Armonk, NY) was used to analyze the collected data. Results The current study comprised 160 patients with acute myocardial infarction; there were 84 (52.5%) who experienced a low level of serum magnesium on admission. Significantly higher proportions of patients who experienced low magnesium levels had diabetes mellitus (P=0.0072) and a history of diuretics (P=0.03) and were administrated beta-blockers (P=0.01), calcium channel blockers (P=0.04), and statins (P=0.007) after admission. Significantly higher proportions of patients with low serum magnesium experienced atrial fibrillation (P=0.03), angina (P=0.03), and cardiogenic shock (P=0.003). Conclusion Low magnesium levels are associated with poor outcomes in most patients admitted with acute myocardial infarction.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.38147