Local impedance tissue characterization to implement pulmonary veins isolation success in AF patients

Abstract Funding Acknowledgements Type of funding sources: None. Background Novel radiofrequency (RF) ablation technology permits local impedance (LI) assessment, enabling increased knowledge of the underlying tissue’s properties. In addition, LI can provide details on catheter tip contact and exten...

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Published in:Europace (London, England) England), 2023-05, Vol.25 (Supplement_1)
Main Authors: Anselmino, M, Lepillier, A, De Sanctis, V, Mazza, A, Zakine, C, Champ-Rigot, L, Santagostino, M, Garnier, F, Bonacchi, G, Di Donna, P, Pandozi, C, Battaglia, A, Malacrida, M, Cosaro, G, Solimene, F
Format: Article
Language:English
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Summary:Abstract Funding Acknowledgements Type of funding sources: None. Background Novel radiofrequency (RF) ablation technology permits local impedance (LI) assessment, enabling increased knowledge of the underlying tissue’s properties. In addition, LI can provide details on catheter tip contact and extent/effectiveness of radiofrequency (RF) delivery. To date, the extent to which left atrial (LA) tissue characterization by LI can guide RF ablation has not yet been explored. Purpose We aimed to assess LI capabilities of predicting RF ablation success in consecutive AF cases with different underlying cardiac tissue characteristics. Methods Two-hundred twelve consecutive patients undergoing de novo AF ablation at 16 European centers were included in the CHARISMA registry. A novel ablation catheter (Stablepoint) with dedicated algorithm (DirectSense) was used to measure LI at the distal electrode. Each ablation point was characterized in terms of RF delivery time, baseline LI and LI drop during ablation according to different atrial substrates: normal-voltage (NV, >0.5mV), intermediate-voltage (IV, 0.1-0.5mV) and low-voltage tissue (LV,
ISSN:1099-5129
1532-2092
DOI:10.1093/europace/euad122.170