Electroceuticals for Neurogastroenterology and Motility Disorders

Purpose of Review To provide an updated overview on use of electrostimulation in gastrointestinal motility disorders and obesity, with a focus on gastric electrical stimulation, vagal nerve stimulation and sacral nerve stimulation. Recent Findings Recent studies on gastric electrical stimulation for...

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Bibliographic Details
Published in:	Current gastroenterology reports 2023-04, Vol.25 (4), p.91-97
Main Authors:	Jiang, Yan, Soffer, Edy
Format:	Article
Language:	eng
Subjects:	Diabetes Drug therapy Electric Stimulation Therapy - methods Gastroenterology Gastrointestinal Diseases - therapy Gastroparesis - therapy Humans Irritable bowel syndrome Medicine Medicine & Public Health Motility Muscle function Nervous system Obesity - therapy Quality of Life Topical Collection on Neurogastroenterology and Motility Disorders of the Gastrointestinal Tract Treatment Outcome Vomiting Vomiting - therapy
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Summary:	Purpose of Review To provide an updated overview on use of electrostimulation in gastrointestinal motility disorders and obesity, with a focus on gastric electrical stimulation, vagal nerve stimulation and sacral nerve stimulation. Recent Findings Recent studies on gastric electrical stimulation for chronic vomiting showed a decrease in frequency of vomiting, but without significant improvement in quality of life. Percutaneous vagal nerve stimulation shows some promise for both symptoms of gastroparesis and IBS. Sacral nerve stimulation does not appear effective for constipation. Studies of electroceuticals for treatment of obesity have quite varied results with less clinical penetrance of the technology. Summary Results of studies on the efficacy of electroceuticals have been variable depending on pathology but this area remains promising. Improved mechanistic understanding, technology and more controlled trials will be helpful to establish a clearer role for electrostimulation in treatment of various GI disorders.
ISSN:	1522-8037 1534-312X