Incomplete cytoreductive surgery for appendiceal and colorectal peritoneal carcinomatosis: Characteristics and outcomes of an overlooked group

Background ond Objectives Complete cytoreductive surgery (CRS) may prolong survival for selected patients with peritoneal carcinomatosis from colorectal cancer (CRC). However, there is a paucity of data on outcomes following incomplete procedures. Methods Patients with incomplete CRS for well‐differ...

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Published in:Journal of surgical oncology 2023-05, Vol.127 (6), p.1028-1034
Main Authors: Goffredo, Paolo, Aguirre, Nicole, Mohamed, Mostafa, Kleiman, David A., Cercek, Andrea, Joshua Smith, J., Paty, Philip B., Weiser, Martin, Garcia‐Aguilar, Julio, Nash, Garrett M.
Format: Article
Language:English
Subjects:
Appendiceal Neoplasms - pathology
Cancer
Colorectal cancer
Colorectal Neoplasms - pathology
Combined Modality Therapy
complications
Cytoreduction Surgical Procedures
Gastric cancer
Humans
Hyperthermia, Induced - adverse effects
incomplete cytoreduction
LAMN
Medical prognosis
metastatic colorectal cancer
outcomes
Peritoneal Neoplasms - therapy
Prognosis
Retrospective Studies
Surgery
Survival Rate
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Summary:Background ond Objectives Complete cytoreductive surgery (CRS) may prolong survival for selected patients with peritoneal carcinomatosis from colorectal cancer (CRC). However, there is a paucity of data on outcomes following incomplete procedures. Methods Patients with incomplete CRS for well‐differentiated (WD) and moderate/poorly‐differentiated (M/PD) appendiceal cancer, right and left CRC were identified at a single tertiary center (2008–2021). Results Of 109 patients, 10% were WD and 51% M/PD appendiceal cancers, and 16% right and 23% left CRC. There were no differences in gender, BMI (mean = 27), ASA score, previous abdominal surgery (72%), and extent of CRS. The PC Index differed between appendiceal and colorectal cancers (mean = 27 vs. 17, p 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.27223