Positive myositis-specific autoantibodies during COVID-19: a case report

Viral infection is known to be a trigger of autoimmune diseases. Numerous cases of coronavirus disease 2019 (COVID-19) with autoimmune manifestations have been reported and several authors have highlighted the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and auto...

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Bibliographic Details
Published in:The Pan African medical journal 2022-12, Vol.43, p.181
Main Authors: Abdelkrim, Asma Ben, Ghozzi, Mariam, Saad, Ghada, Melayah, Sarra, Ach, Taieb, Ghedira, Ibtissem, Ach, Koussay
Format: Article
Language:English
Subjects:
Adult
Autoantibodies
Autoimmune Diseases
Case Report
COVID-19 - complications
Female
Humans
Myositis - diagnosis
Myositis - drug therapy
SARS-CoV-2
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Summary:Viral infection is known to be a trigger of autoimmune diseases. Numerous cases of coronavirus disease 2019 (COVID-19) with autoimmune manifestations have been reported and several authors have highlighted the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and autoimmune diseases. Autoimmune myopathies being one of these manifestations. A 27-year-old diabetic woman was admitted for management of acido-ketosis decompensation of her diabetes secondary to SARS-CoV-2 infection. During hospitalization, she developed muscle weakness and increased creatine kinase levels, which led us to assay the autoimmunity pattern which became positive for myositis-specific autoantibodies against single recognition particle (anti-SRP). The patient was treated with intense hydration with clinical and biological improvement and anti-SRP disappeared two months later. Positive myositis auto-antibodies are one of the autoimmune complications that could be seen during and after the SARS-CoV-2 infection.
ISSN:1937-8688
1937-8688
DOI:10.11604/PAMJ.2022.43.181.36322