The effects of greater frequency of two most prevalent bothersome acute respiratory symptoms on health-related quality of life in the 2020 US general population

Purpose Upper respiratory tract infections (URTI) and related symptoms are widespread and a common reason for visiting primary care with cough and sore throat being most prevalent. Despite their impact on daily activities, no studies have explored the impact on health-related quality of life (HRQOL)...

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Bibliographic Details
Published in:Quality of life research 2023-04, Vol.32 (4), p.1043-1051
Main Authors: Ware, John E., Coutinho, Graça, Smith, Adam B., Tselenti, Evi, Kulasekaran, Anuradha
Format: Article
Language:English
Subjects:
Adult
Analysis of covariance
Chronic obstructive pulmonary disease
Cough - epidemiology
Health Surveys
Humans
Infections
Medicine
Medicine & Public Health
Middle Aged
Pharyngitis - epidemiology
Primary care
Public Health
Quality of life
Quality of Life - psychology
Quality of Life Research
Respiratory Tract Infections - epidemiology
Sociology
Viral infections
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Summary:Purpose Upper respiratory tract infections (URTI) and related symptoms are widespread and a common reason for visiting primary care with cough and sore throat being most prevalent. Despite their impact on daily activities, no studies have explored the impact on health-related quality of life (HRQOL) in representative general populations. We aimed to understand the short-term impact of the two most prevalent URTI symptoms on HRQOL. Methods Online 2020 surveys including acute (≤ 4 weeks) respiratory symptoms (sore throat and cough) and SF-36 ® health survey (all with 4-week recall) were analysed using analysis of covariance (ANCOVA) in comparison with adult US population norms. Linear T-score transformation of SF-6D utility (ranging from 0 to 1) enabled direct comparisons with SF-36. Results In total, 7563 US adults responded (average age: 52 years; range: 18–100 years). Sore throat and cough lasting at least several days were experienced by 14% and 22% participants, respectively. Chronic respiratory conditions were reported by 22% of the sample. A clear and consistent pattern of group HRQOL means declining significantly ( p  
ISSN:0962-9343
1573-2649
DOI:10.1007/s11136-022-03319-4