Aluminum Exposure and Metabolism

Abstract Aluminum (A1) is a nonessential, toxic metal to which humans are frequently exposed. oral exposure to aluminum occurs through ingestion of aluminum-containing pharmaceuticals and to a lesser extent foods and water. Parented exposure to aluminum can occur via contaminated total parented nutr...

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Bibliographic Details
Published in:Critical reviews in clinical laboratory sciences 1997, Vol.34 (5), p.439-474
Main Authors: Greger, J. L., Sutherland, Jessica E., Yokel, Robert
Format: Article
Language:English
Subjects:
Absorption
Aluminum
Aluminum - pharmacokinetics
Aluminum - poisoning
Aluminum - urine
bile
Bile - metabolism
Calcium
Citrate
Diet
Digestive System - metabolism
Drug Contamination
Environmental Exposure
Exposure
Food Contamination
Humans
iron. Transfemn
Metabolism
Pharmaceuticals
Respiratory System - metabolism
Skin - metabolism
tissue turnover
toxicity
urine
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Summary:Abstract Aluminum (A1) is a nonessential, toxic metal to which humans are frequently exposed. oral exposure to aluminum occurs through ingestion of aluminum-containing pharmaceuticals and to a lesser extent foods and water. Parented exposure to aluminum can occur via contaminated total parented nutrition (TPN). intravenous (iv) solutions, or contaminated dialysates. Inhalation exposure may be important in some occupational settings. The gut is the most effective organ in preventing tissue aluminum accumulation after oral exposure. Typically gastrointestinal absorption of aluminum from diets is
ISSN:1040-8363
1549-781X
DOI:10.3109/10408369709006422