SAMAY S24: a novel wireless 'online' device for real-time monitoring and analysis of volumetric capnography

Volumetric capnography (VCap) provides information about CO 2 exhaled per breath (VCO 2 br) and physiologic dead space (VDphys). A novel wireless device with a high response time CO 2 mainstream sensor coupled with a digital flowmeter was designed to monitor all VCap parameters online in rabbits (SA...

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Bibliographic Details
Main Authors: Vallarino, M., Quintela, L., Jorge, G., Lorenzo, G., Nan, C., Isper, M., Bouchacourt, J.P., Grignola, J.C.
Format: Conference Proceeding
Language:English
Subjects:
airway dead space
Algorithms
alveolar dead space
Animals
Capnography - methods
Carbon Dioxide
Enghoff index
Lung
physiological dead space
Rabbits
Real-time systems
Respiratory Dead Space - physiology
Shape
Software
Time factors
volumetric capnography
Wireless communication
Wireless sensor networks
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Summary:Volumetric capnography (VCap) provides information about CO 2 exhaled per breath (VCO 2 br) and physiologic dead space (VDphys). A novel wireless device with a high response time CO 2 mainstream sensor coupled with a digital flowmeter was designed to monitor all VCap parameters online in rabbits (SAMAY S24).Ten New Zealand rabbits were anesthetized and mechanically ventilated. VCO 2 br corresponds to the area under the VCap curve. We used the modified Langley method to assess the airway VD (VDaw) and the alveolar CO 2 pressure. VDphys was estimated using Bohr's formula, and the alveolar VD was calculated by subtracting VDaw from VDphys. We compared (Bland-Altman) the critical VCap parameters obtained by SAMAY S24 (Langley) with the Functional Approximation based on the Levenberg-Marquardt Algorithm (FA-LMA) approach during closed and opened chest conditions.SAMAY S24 could assess dead space volumes and VCap shape in real time with similar accuracy and precision compared to the 'offline' FA-LMA approach. The opened chest condition impaired CO 2 kinetics, decreasing the phase II slope, which was correlated with the volume of CO 2 exhaled per minute.
ISSN:2694-0604
DOI:10.1109/EMBC40787.2023.10340680