Influence of blood pressure variations during hemodialysis on the prognosis of dialysis patients

The prognosis of dialysis patients is poorer than that of the general population. The relationship between dialysis patients' blood pressure (BP) and mortality is controversial. We investigated the relationships between mortality and (i) pre-dialysis BP and (ii) BP variation during hemodialysis...

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Bibliographic Details
Published in:Clinical and experimental hypertension (1993) 2023-12, Vol.45 (1), p.2236336-2236336
Main Authors: Ohta, Yuko, Fukuhara, Masayo, Fujisawa, Ritsuko, Kanesaki, Maki, Tsuruta, Hiroshi, Nakamura, Hidetoshi, Kawano, Yuhei
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Blood Pressure - physiology
Dialysis
Dialysis patient
Humans
Hypotension - epidemiology
Hypotension - etiology
intradialytic hypotension
Kidney Failure, Chronic - therapy
Middle Aged
mortality
pre-dialysis systolic blood pressure
Prognosis
Renal Dialysis - adverse effects
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Summary:The prognosis of dialysis patients is poorer than that of the general population. The relationship between dialysis patients' blood pressure (BP) and mortality is controversial. We investigated the relationships between mortality and (i) pre-dialysis BP and (ii) BP variation during hemodialysis in maintenance dialysis patients. We retroactively analyzed the cases of the 284 patients on hemodialysis (mean age 68 ± 13 years old) who had been regularly followed at Kokura Daiichi Hospital, Japan in 2018. We assessed the relationship between the patients' BP components and risk of mortality over a 40-month follow-up. The patients' average systolic/diastolic BP values before dialysis in 2018 were 145 ± 18/77 ± 11, and those after dialysis were 129 ± 17/71 ± 10 mmHg. The prevalence of intradialytic hypotension was 46.8%. During an average follow-up of 35 months, 72 patients died, including from infectious diseases (n = 41), cardiovascular diseases (n = 9), malignancies (n = 5), and others (n = 17). The mortality rate was 32.7% in the pre-dialysis SBP 
ISSN:1064-1963
1525-6006
DOI:10.1080/10641963.2023.2236336