The Combined Effect of Tropicamide and Phenylephrine on Corneal Astigmatism Axis

To analyze astigmatism axis changes after tropicamide and phenylephrine combined instillation. One hundred and thirty-one eyes from 66 patients enrolled this cross-sectional study. An extensive ocular examination was carried out prior to tropicamide and phenylephrine instillation. Power and axis val...

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Bibliographic Details
Published in:Current eye research 2022-02, Vol.47 (2), p.179-186
Main Authors: Sánchez-González, José-María, Flikier, David, Nebro-Cobos, Salvador, Zamorano-Martín, Francisco, Rachwani-Anil, Rahul, García-Lorente, María, Borroni, Davide, Peraza-Nieves, Jorge, Rocha-de-Lossada, Carlos
Format: Article
Language:English
Subjects:
astigmatism
Astigmatism - diagnosis
Astigmatism - surgery
axis
Cornea - surgery
Corneal Diseases
Corneal Topography - methods
Cross-Sectional Studies
Humans
Phenylephrine
Tropicamide
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Summary:To analyze astigmatism axis changes after tropicamide and phenylephrine combined instillation. One hundred and thirty-one eyes from 66 patients enrolled this cross-sectional study. An extensive ocular examination was carried out prior to tropicamide and phenylephrine instillation. Power and axis value from flat, steep, and mean keratometry were calculated using an Auto Kerato-Refractometer (AKR). Later, topography and tomography maps were evaluated with Pentacam HR® (Oculus, Wetzlar, Germany). Subsequently, a single drop of tropicamide 1% and phenylephrine hydrochloride 10% were instilled twice, with a five-minute gap between each instillation. After 30 minutes, the AKR and Pentacam HR® tests were repeated. Incyclotorsion was found in 59 eyes (45.1%) and mean absolute incyclotorsion change was 3.91 ± 3.62 degrees (0.10 to 14.20). Excyclotorsion was found in 72 eyes (54.9%) and mean excyclotorsion change was 4.99 ± 5.94 degrees (0.20 to 36.20). We observed that 74.6% and 68.1% of eyes experienced incyclotorsion and excyclotorsion within 0 to 5 degrees, respectively. Fewer patients experienced incyclotorsion and excyclotorsion changes within 5 to 10 degrees, precisely 11.8% and 19.4%, respectively. Eyes that experienced over 10 degrees of incyclotorsion and excyclotorsion were 13.6% and 12.5%, respectively. Astigmatism axis could change after combined tropicamide and phenylephrine instillation. Reference axis marking in astigmatism correction surgery should be performed under the same circumstances as the astigmatism axis has been measured.
ISSN:0271-3683
1460-2202
DOI:10.1080/02713683.2021.1971720