Chitosan and Derivatives: Bioactivities and Application in Foods

Chitosan is a biodegradable, biocompatible, and nontoxic aminopolysaccharide. This review summarizes and discusses the structural modifications, including substitution, grafting copolymerization, cross-linking, and hydrolysis, utilized to improve the physicochemical properties and enhance the bioact...

Full description

Saved in:
Bibliographic Details
Published in:Annual review of food science and technology 2021-03, Vol.12 (1), p.407-432
Main Authors: Zhou, Da-Yong, Wu, Zi-Xuan, Yin, Fa-Wen, Song, Shuang, Li, Ao, Zhu, Bei-Wei, Yu, Liang-Li (Lucy)
Format: Article
Language:English
Subjects:
application
biological activity
chitosan
derivatives
functionality
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chitosan is a biodegradable, biocompatible, and nontoxic aminopolysaccharide. This review summarizes and discusses the structural modifications, including substitution, grafting copolymerization, cross-linking, and hydrolysis, utilized to improve the physicochemical properties and enhance the bioactivity and functionality of chitosan and related materials. This manuscript also reviews the current progress and potential of chitosan and its derivatives in body-weight management and antihyperlipidemic, antihyperglycemic, antihypertensive, antimicrobial antioxidant, anti-inflammatory, and immunostimulatory activities as well as their ability to interact with gut microbiota. In addition, the potential of chitosan and its derivatives as functional ingredients in food systems, such as film and coating materials, and delivery systems is discussed. This manuscript aims to provide up-to-date information to stimulate future discussion and research to promote the value-added utilization of chitosan in improving the safety, quality, nutritional value and health benefits, and sustainability of our food system while reducing the environmental hazards.
ISSN:1941-1413
1941-1421
DOI:10.1146/annurev-food-070720-112725