New Terpenoids And Lignans From The Twigs Of Tripterygium Hypoglaucum

New Terpenoids And Lignans From The Twigs Of Tripterygium Hypoglaucum

Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9′-O-benzoyl-lariciresinol (4) showed weak cytotoxicity ag...

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Bibliographic Details
Published in:Natural product research 2020-07, Vol.34 (13), p.1853-1861
Main Authors: Zheng, Hui, Wang, Li, Yang, Tao, Liu, Dan, Li, Hong-Mei, Chen, Xuan-Qin, Li, Rong-Tao
Format: Article
Language:eng
Subjects:
Celastraceae
Cytotoxicity
Ethanol
lignan
Lignans
Terpenes
terpenoid
Toxicity
Tripterygium
Tripterygium hypoglaucum
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Summary:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9′-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cells, with an IC 50 value of 30.1 μM in vitro.
ISSN:1478-6419
1478-6427