Women have right ventricular infarction more frequently than men

Objective The objective of the study was to determine whether women signifi cantly have more frequently right ventricular infarction than men. Methods The study population consisted of consecutive patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous int...

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Bibliographic Details
Published in:Acta Cardiologica 2015-06, Vol.70 (3), p.343-349
Main Authors: Obradovic, Slobodan, Dzudovic, Boris, Djuric, Ivica, Jovic, Zoran, Djenic, Nemanja
Format: Article
Language:English
Subjects:
Aged
Female
gender
Heart Ventricles
Humans
inferior wall myocardial infarction
Male
Middle Aged
Myocardial Infarction - diagnosis
Myocardial Infarction - epidemiology
Odds Ratio
RVI
Sex Factors
STEMI
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Summary:Objective The objective of the study was to determine whether women signifi cantly have more frequently right ventricular infarction than men. Methods The study population consisted of consecutive patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous intervention. The following criteria were used for the diagnosis of right ventricular infarction: ST-segment elevation in one of the right precordial leads V4R-V6R for equal or more than 1 mm together with ST-segment elevation in at least two contiguous inferior leads. The odds ratio for the diagnosis was calculated according to gender. Searching PubMed, nine more relevant studies that used the same criteria for the diagnosis of right ventricular infarction were identifi ed and a meta-analysis was conducted. Results In our group of 517 consecutive patients with STEMI, 32 (23.5%) of 136 women and 42 (11.0%) of 381 men had RVI (odds ratio (OR) = 2.48, 95% confi dence interval (CI): 1.49-4.13; P= 0.001). Two hundred and seventy-fi ve patients had inferior STEMI and among them 32 (42.7%) of 75 women and 42 (23.1%) of 182 men, had a right ventricular infarction (OR = 2.48, 95%CI: 1.40-4.40; P= 0.002). In a meta-analysis, a total number of 4,326 patients with inferior STEMI were included. Four hundred and thirty-seven (41.4%) out of 1,056 women and 1,221 (37.3%) out of 3,270 men, had been diagnosed with RVI (OR = 1.27, 95%CI: 1.09 - 1.48; P= 0.021). Conclusion Right ventricular infarctions occur more frequently in women than in men.
ISSN:0001-5385
1784-973X
0373-7934
DOI:10.1080/AC.70.3.3080639