Evaluation of a Commercial Microarray System for Detection of SHV-, TEM-, CTX-M-, and KPC-Type β-Lactamase Genes in Gram-Negative Isolates

We evaluated the ability of a commercial microarray system (Check KPC/ESBL; Check-Points Health BV) to detect clinically important class A β-lactamase genes. A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for blaSHV, 9...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Clinical Microbiology 2010-07, Vol.48 (7), p.2618-2622
Main Authors: Endimiani, Andrea, Hujer, Andrea M, Hujer, Kristine M, Gatta, Julian A, Schriver, Andrew C, Jacobs, Michael R, Rice, Louis B, Bonomo, Robert A
Format: Article
Language:eng
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We evaluated the ability of a commercial microarray system (Check KPC/ESBL; Check-Points Health BV) to detect clinically important class A β-lactamase genes. A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for blaSHV, 98.8% and 100%; for blaTEM, 100% and 96.4%; and for blaCTX₋M and blaKPC, 100% and 100%.
ISSN:0095-1137
1098-660X