Solitary Eosinophilic Granuloma of the Third Metacarpal at Pediatric Age

Langerhans cell histiocytosis involves disorders previously referred to as "histiocytosis X" (including eosinophilic granuloma of bone, Letterer-Siwe, and Hand-Schüller-Christian syndrome). Eosinophilic granuloma of the hand, especially if solitary, is extremely rare. This is the third ped...

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Bibliographic Details
Published in:Pediatric hematology and oncology 2003, Vol.20 (8), p.589-595
Main Authors: Demiral, Ayse N., Özdemir, Oguz, Coskunol, Erhan, Bacakoglu, Abdülkadir, Çevikol, Can, Basdemir, Gülçin
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child, Preschool
Eosinophilic Granuloma
Eosinophilic Granuloma - diagnostic imaging
Eosinophilic Granuloma - pathology
Eosinophilic Granuloma - radiotherapy
Female
Hand
Hematologic and hematopoietic diseases
Humans
Medical sciences
Metacarpus
Other diseases. Hematologic involvement in other diseases
Pediatric
Radiography
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Description
Summary:Langerhans cell histiocytosis involves disorders previously referred to as "histiocytosis X" (including eosinophilic granuloma of bone, Letterer-Siwe, and Hand-Schüller-Christian syndrome). Eosinophilic granuloma of the hand, especially if solitary, is extremely rare. This is the third pediatric case reported in the literature with solitary eosinophilic granuloma of the hand and the second with metacarpal involvement. The patient's lesion was curetted and the histologic examination showed eosinophilic granuloma. The patient received adjuvant radiotherapy because of continuing mild functional impairment and fracture risk. At 12-month follow-up near complete recovery of the lesion was observed. Radiologically, there was sclerosis and remodeling of the third metacarpal. The patient is disease-free at 26 months.
ISSN:0888-0018
1521-0669
DOI:10.1080/08880010390242933