Prinzmetal's Variant Angina During Cis-Diamminodichloroplatinum (CDDP) Administration: Case Report

We report a rare case, the second in the literature, of Prinzmetal's Variant Angina (VA) caused by cis-diamminodichloroplatinum (CDDP) infusion. We also discuss the possible underlying mechanism of ischemia.

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Bibliographic Details
Published in:Journal of chemotherapy (Florence) 2003-02, Vol.15 (1), p.89-90
Main Authors: Oliva, S., Mannarini, A., Giotta, F., Colucci, G., Calabrese, P.
Format: Article
Language:English
Subjects:
Angina Pectoris, Variant - chemically induced
Antineoplastic Agents - adverse effects
Antineoplastic Agents - therapeutic use
Biological and medical sciences
Carcinoma, Non-Small-Cell Lung - drug therapy
Cisplatin - adverse effects
Cisplatin - therapeutic use
Drug toxicity and drugs side effects treatment
Electrocardiography
Humans
Lung Neoplasms - drug therapy
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Toxicity: cardiovascular system
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Description
Summary:We report a rare case, the second in the literature, of Prinzmetal's Variant Angina (VA) caused by cis-diamminodichloroplatinum (CDDP) infusion. We also discuss the possible underlying mechanism of ischemia.
ISSN:1120-009X
1973-9478
DOI:10.1179/joc.2003.15.1.89