Resting energy expenditure-fat-free mass relationship: new insights provided by body composition modeling

Obesity Research Center, St. Luke's-Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, New York 10025 The relationship between resting energy expenditure (REE) and metabolically active fat-free mass (FFM) is a cornerstone in the study of physiological aspects...

Full description

Saved in:
Bibliographic Details
Published in:American journal of physiology: endocrinology and metabolism 2000-09, Vol.279 (3), p.E539-E545
Main Authors: Wang, Zimian, Heshka, Stanley, Gallagher, Dympna, Boozer, Carol N, Kotler, Donald P, Heymsfield, Steven B
Format: Article
Language:English
Subjects:
Algorithms
Body Composition - physiology
Energy Metabolism - physiology
Humans
Models, Biological
Rest - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Obesity Research Center, St. Luke's-Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, New York 10025 The relationship between resting energy expenditure (REE) and metabolically active fat-free mass (FFM) is a cornerstone in the study of physiological aspects of body weight regulation and human energy requirements. Important questions, however, remain unanswered regarding the observed linear REE-FFM association in adult humans. This led us to develop a series of REE-body composition models that provide insights into the widely used simple linear REE-FFM prediction model derived experimentally in adult humans. The new models suggest that the REE-FFM relationship in mammals as a whole is curvilinear, that a segment of this function within a FFM range characteristic of adult humans can be fit with a linear equation almost identical to that observed from a composite review of earlier human studies, and that mammals as a whole exhibit a decrease in the proportion of FFM as high metabolic rate organs with greater FFM. The present study thus provides a new approach for examining REE-FFM relationships, advances in a quantitative manner previously observed albeit incompletely formulated REE-body composition associations, and identifies areas in need of additional research. energy metabolism; body composition
ISSN:0193-1849
1522-1555
DOI:10.1152/ajpendo.2000.279.3.e539