Carrier-Mediated Delivery of 9-(2-Phosphonylmethoxyethyl)Adenine to Parenchymal Liver Cells: a Novel Therapeutic Approach for Hepatitis B

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Published in:Antimicrobial Agents and Chemotherapy 2000-03, Vol.44 (3), p.477-483
Main Authors: DE VRUEH, R. L. A, RUMP, E. T, VAN DE BILT, E, VAN VEGHEL, R, BALZARINI, J, BIESSEN, E. A. L, VAN BERKEL, T. J. C, BIJSTERBOSCH, M. K
Format: Article
Language:English
Subjects:
9-(2-phosphonylmethoxyethyl)adenine
Adenine
Adenine - administration & dosage
Adenine - analogs & derivatives
Adenine - blood
Adenine - chemistry
Adenine - pharmacokinetics
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral Agents
Antiviral Agents - administration & dosage
Antiviral Agents - blood
Antiviral Agents - chemistry
Antiviral Agents - pharmacokinetics
Biological and medical sciences
Chromatography - methods
Drug Carriers
Hepatitis B
Hepatitis B - drug therapy
Hepatitis B virus
Lipoproteins, HDL - metabolism
Lithocholic Acid - analogs & derivatives
Lithocholic Acid - chemical synthesis
Lithocholic Acid - metabolism
Lithocholic Acid - pharmacology
Liver
Liver - cytology
Liver - drug effects
Liver - metabolism
Male
Medical sciences
Organophosphonates
Pharmacology
Pharmacology. Drug treatments
Prodrugs - administration & dosage
Prodrugs - chemical synthesis
Prodrugs - pharmacokinetics
Rats
Rats, Wistar
Tissue Distribution
Tritium
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.44.3.477-483.2000