Neonatal Intensive Care Unit Candidemia: Epidemiology, Risk Factors, Outcome, and Critical Review of Published Case Series

Evaluation of epidemiological trends, risk factors, and clinical outcome associated with candidemia at a neonatal intensive care unit is reported. From January 2005 to December 2009, forty candidemia cases were identified. C. albicans and C. parapsilosis were the most common species recovered (69 an...

Full description

Saved in:
Bibliographic Details
Published in:Mycopathologia (1975) 2012-04, Vol.173 (4), p.219-228
Main Authors: Spiliopoulou, A., Dimitriou, G., Jelastopulu, E., Giannakopoulos, I., Anastassiou, E. D., Christofidou, Myrto
Format: Article
Language:English
Subjects:
Antibiotics
Antifungal agents
Antifungal Agents - therapeutic use
azoles
Bacteremia
Biomedical and Life Sciences
Birth weight
Candida
Candida - isolation & purification
Candidemia
Candidemia - complications
Candidemia - drug therapy
Candidemia - epidemiology
Cross Infection - complications
Cross Infection - drug therapy
Cross Infection - epidemiology
Epidemiology
Eukaryotic Microbiology
Female
Gestational age
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases - drug therapy
Infant, Newborn, Diseases - epidemiology
Infants (Newborn)
Intensive care units
Intensive Care Units, Neonatal - statistics & numerical data
Intubation
Life Sciences
Male
Medical Microbiology
Microbial Ecology
Microbiology
Mortality
Neonates
Nutrition
Parenteral nutrition
Patient outcomes
Plant Sciences
Renal failure
Retrospective Studies
Risk Factors
Steroid hormones
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Evaluation of epidemiological trends, risk factors, and clinical outcome associated with candidemia at a neonatal intensive care unit is reported. From January 2005 to December 2009, forty candidemia cases were identified. C. albicans and C. parapsilosis were the most common species recovered (69 and 24%, respectively). All C. parapsilosis strains were susceptible to antifungals, whereas, C. albicans exhibited higher resistance rates to azoles. Low birth weight, low gestational age, presence of central lines, endotracheal intubation, total parenteral nutrition, previous use of antibiotics, steroids, previous episode(s) of bacteremia and prolonged stay in intensive care unit were common features associated with candidemia. C. albicans was most often isolated from extremely low birth weight neonates as compared to non- albicans Candida ( P  
ISSN:0301-486X
1573-0832
DOI:10.1007/s11046-011-9498-3