A case report of a patient with rheumatoid arthritis complicated with Mycobacterium avium during tocilizumab treatment

A female patient with rheumatoid arthritis (RA) suffered from Mycobacterium avium ( M. avium ) infection during tocilizumab treatment. Tocilizumab was discontinued and she was treated with a recommended chemotherapy, resulting in improvement of M. avium . Tocilizumab retreatment did not aggravate M....

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Bibliographic Details
Published in:Modern rheumatology 2011-12, Vol.21 (6), p.655-659
Main Authors: Nakahara, Hideko, Kamide, Yosuke, Hamano, Yoshimasa, Hosokawa, Takashi, Nishide, Masayuki, Lin, Yu, Kawamoto, Keisuke, Fusama, Mie, Higa, Shinji, Kuroiwa, Takashi, Igarashi, Tsuyoshi, Kuritani, Taro, Maeda, Keiji
Format: Article
Language:English
Subjects:
Bacterial infections
Case management
Case Report
Case reports
Chemotherapy
Drug therapy
Infection
Medicine
Medicine & Public Health
Mycobacterium avium
Orthopedics
Rheumatoid arthritis
Rheumatology
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Description
Summary:A female patient with rheumatoid arthritis (RA) suffered from Mycobacterium avium ( M. avium ) infection during tocilizumab treatment. Tocilizumab was discontinued and she was treated with a recommended chemotherapy, resulting in improvement of M. avium . Tocilizumab retreatment did not aggravate M. avium infection, and radiographic abnormalities improved over 1 year after cessation of the recommended therapy. Tocilizumab may be one candidate for intractable RA patients with M. avium if any biologic is required.
ISSN:1439-7595
1439-7609
DOI:10.1007/s10165-011-0448-1