Cardiovascular risk factors and noninvasive assessment of arterial structure and function in obese Turkish children

Obesity is associated with a number of risk factors, such as hyperlipidemia, hyperinsulinemia, hypertension, and early atherosclerosis. Evidence indicates that atherosclerosis begins in childhood and progresses over decades. In this work, we examined the relationship between cardiovascular risk fact...

Full description

Saved in:
Bibliographic Details
Published in:European journal of pediatrics 2010-10, Vol.169 (10), p.1241-1248
Main Authors: Yilmazer, Murat Muhtar, Tavli, Vedide, Carti, Özgür Umaç, Mese, Timur, Güven, Barış, Aydın, Banu, Devrim, Ilker, Tavlı, Talat
Format: Article
Language:English
Subjects:
Adolescent
Atherosclerosis
Atherosclerosis - diagnostic imaging
Atherosclerosis - epidemiology
Atherosclerosis - physiopathology
Biological and medical sciences
Biomarkers - blood
Blood pressure
Body Mass Index
Brachial Artery - diagnostic imaging
Brachial Artery - physiopathology
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Carotid arteries
Carotid Arteries - diagnostic imaging
Carotid Arteries - physiopathology
Chi-Square Distribution
Child
Children & youth
Cholesterol
Compliance
Coronary heart disease
Epidemiology
Female
General aspects
Glucose
Hair
Heart
High density lipoprotein
Humans
Hyperlipidemia
Hypertension
Hypertriglyceridemia - physiopathology
Immunoassay
Linear Models
Male
Medical sciences
Medicine
Medicine & Public Health
Obesity
Obesity - epidemiology
Obesity - physiopathology
Original Paper
Pediatrics
Public health. Hygiene
Public health. Hygiene-occupational medicine
Reproducibility of Results
Risk Factors
Statistics, Nonparametric
Teenagers
Tunica Intima - diagnostic imaging
Tunica Intima - physiopathology
Turkey - epidemiology
Ultrasonic imaging
Ultrasonography
Veins & arteries
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Obesity is associated with a number of risk factors, such as hyperlipidemia, hyperinsulinemia, hypertension, and early atherosclerosis. Evidence indicates that atherosclerosis begins in childhood and progresses over decades. In this work, we examined the relationship between cardiovascular risk factors and ultrasonographic signs of subclinical atherosclerosis in 77 obese children and adolescents compared to 40 non-obese healthy peers. Carotis intima media thickness (cIMT), carotid artery compliance (CAC), brachial artery flow-mediated dilatation (FMD), and established cardiovascular risk factors were studied. In the obese patients, cIMT was significantly increased (0.57 mm vs 0.45 mm, p  
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-010-1216-5