Hemodynamic and Biochemical Characteristics of the Prefrontal Cortex after First Episodes of Juvenile Schizophrenia

The biochemical (proton MR spectroscopy data) and hemodynamic (fMRI data) characteristics of the functional state of the prefrontal cortex were studied in seven patients with juvenile episodic schizophrenia in the state of remission after the first episode and in eight healthy subjects of similar ge...

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Bibliographic Details
Published in:Neuroscience and behavioral physiology 2011-10, Vol.41 (8), p.883-888
Main Authors: Lebedeva, I. S., Semenova, N. A., Kaleda, V. G., Akhadov, T. A., Barkhatova, A. N., Petryaikin, A. V., Petryaikin, F. A., Mitrofanov, A. A., Kupriyanov, D. A.
Format: Article
Language:English
Subjects:
Age
Behavioral Sciences
Biochemical characteristics
Biomedical and Life Sciences
Biomedicine
Cortex (prefrontal)
Data processing
Functional magnetic resonance imaging
Gender
Hemodynamics
Magnetic resonance spectroscopy
Mental disorders
Mental health
Nervous system
Neurobiology
Neurosciences
Protons
Psychopathology
Remission
Remission (Medicine)
Schizophrenia
Spectrum analysis
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Summary:The biochemical (proton MR spectroscopy data) and hemodynamic (fMRI data) characteristics of the functional state of the prefrontal cortex were studied in seven patients with juvenile episodic schizophrenia in the state of remission after the first episode and in eight healthy subjects of similar gender and age. There were no differences between groups in terms of the parameters studied, though parameters were related to the severity of psychopathological symptomatology in patients, as evaluated on the PANSS.
ISSN:0097-0549
1573-899X
DOI:10.1007/s11055-011-9503-9