Synthetic applications of benzothiazole containing cyanoacetyl group

The reactions of 2-(benzo[d]thiazol-2-yl)-3-oxopentanedinitrile with a variety of reagents have been investigated aiming to explore the synthetic potentialities of this activated nitrile in heterocyclic synthesis. Several novel pyridopyrimidine, chromenopyridine, oxazole, diazepinone, thiophene and...

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Bibliographic Details
Published in:European journal of chemistry 2010-06, Vol.1 (2), p.90-95
Main Authors: Fadda, Ahmed Ali, Abdelrazek, Fathy Mohamed, Mohamed, Khaled Samir, Ghieth, Howayda Mohamed Mostafa, Etman, Hassan Ali
Format: Article
Language:English
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Summary:The reactions of 2-(benzo[d]thiazol-2-yl)-3-oxopentanedinitrile with a variety of reagents have been investigated aiming to explore the synthetic potentialities of this activated nitrile in heterocyclic synthesis. Several novel pyridopyrimidine, chromenopyridine, oxazole, diazepinone, thiophene and thienopyridine derivatives could be obtained starting from 2-(benzo[d]thiazol-2-yl)-3-oxopentanedinitrile and plausible mechanisms for their formations are reported.
ISSN:2153-2249
2153-2257
DOI:10.5155/eurjchem.1.2.90-95.32