Clinicopathological analysis of head and neck chondrosarcoma: three case reports and literature review

Abstract Chondrosarcoma (CHS) is a malignant neoplasm characterized by the formation of cartilaginous matrix by neoplastic cells, with a high propensity for local recurrences. Head and neck CHS is rare, accounting for less than 12% of all cases of CHS, usually affecting the maxilla. The majority of...

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Bibliographic Details
Published in:International journal of oral and maxillofacial surgery 2012-02, Vol.41 (2), p.203-210
Main Authors: Pontes, H.A.R, Pontes, F.S.C, de Abreu, M.C, de Carvalho, P.L, de Brito Kato, A.M, Fonseca, F.P, de Freitas Silva, B.S, Neto, N.C
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
bone tumours
chondrosarcoma
Chondrosarcoma - pathology
Chondrosarcoma - secondary
Dentistry
Diagnosis, Differential
Diseases of the osteoarticular system
Female
Fibrous Dysplasia of Bone - diagnosis
Follow-Up Studies
Humans
Male
Mandibular Neoplasms - pathology
Maxillary Diseases - diagnosis
Maxillary Neoplasms - pathology
Medical sciences
metastasis
Neoplasm Grading
Neoplasm Recurrence, Local - pathology
Otorhinolaryngology. Stomatology
Radiography, Bitewing
Radiography, Panoramic
Surgery
Tomography, X-Ray Computed
Tumors of striated muscle and skeleton
Young Adult
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Summary:Abstract Chondrosarcoma (CHS) is a malignant neoplasm characterized by the formation of cartilaginous matrix by neoplastic cells, with a high propensity for local recurrences. Head and neck CHS is rare, accounting for less than 12% of all cases of CHS, usually affecting the maxilla. The majority of affected patients are in the fourth decade of life, with a slight predilection for male patients. A painless swelling is commonly the most frequent complaint. Surgery with wide en-bloc resection is the preferred treatment for CHS; radiotherapy and chemotherapy are usually palliative options. Owing to its rarity, there are few clinical series evaluating the biological behaviour of head and neck CHS. The aim of this study is to analyse the clinicopathological characteristics of head and neck CHS by reporting 3 new cases of this neoplasia affecting the jaw bones and reviewing the clinical series previously published in the English literature.
ISSN:0901-5027
1399-0020
DOI:10.1016/j.ijom.2011.10.002