Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes

Aims/hypothesis We investigated whether objectively measured sedentary time and interruptions in sedentary time are associated with metabolic factors in people with type 2 diabetes. Methods We studied 528 adults (30–80 years) with newly diagnosed type 2 diabetes, who were participants in a diet and...

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Bibliographic Details
Published in:Diabetologia 2012-03, Vol.55 (3), p.589-599
Main Authors: Cooper, A. R., Sebire, S., Montgomery, A. A., Peters, T. J., Sharp, D. J., Jackson, N., Fitzsimons, K., Dayan, C. M., Andrews, R. C.
Format: Article
Language:English
Subjects:
Adult
Aerobics
Aged
Aged, 80 and over
Behavior
Biological and medical sciences
Body Mass Index
Cholesterol
Cholesterol, HDL - blood
Cohort Studies
Cross-Sectional Studies
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - metabolism
Diabetes Mellitus, Type 2 - therapy
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
England
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Exercise
Female
Glucose
Human Physiology
Humans
Insulin - blood
Insulin Resistance
Internal Medicine
Lifestyles
Longitudinal Studies
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Metabolism
Middle Aged
Motor Activity
Nutrition
Overweight - complications
Patient Compliance
Physical fitness
Sedentary Lifestyle
Time Factors
Young Adult
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Summary:Aims/hypothesis We investigated whether objectively measured sedentary time and interruptions in sedentary time are associated with metabolic factors in people with type 2 diabetes. Methods We studied 528 adults (30–80 years) with newly diagnosed type 2 diabetes, who were participants in a diet and physical activity intervention. Waist circumference (WC), fasting HDL-cholesterol, insulin and glucose levels, HOMA of insulin resistance (HOMA-IR) and physical activity (accelerometer) were measured at baseline and at 6 months follow-up. Linear regression models were used to investigate cross-sectional and longitudinal associations of accelerometer-derived sedentary time and breaks in sedentary time (BST) with metabolic variables. Results In cross-sectional analyses each hour of sedentary time was associated with larger WC (unstandardised regression coefficient [ B ] [95% CI] 1.89 cm [0.94, 2.83]; p  
ISSN:0012-186X
1432-0428
DOI:10.1007/s00125-011-2408-x