Foxo1 and Foxo3 help Foxp3

In this issue of Immunity, Kerdiles et al. (2010) report that Foxo transcription factors are essential for the development and function of Foxp3-expressing regulatory T (Treg) cells via controlling the expression of genes associated with Treg cell function.

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Bibliographic Details
Published in:Immunity (Cambridge, Mass.) Mass.), 2010-12, Vol.33 (6), p.835-837
Main Authors: Ohkura, Naganari, Sakaguchi, Shimon
Format: Article
Language:English
Subjects:
Cell cycle
Cytokines
FOXO1 protein
Gene expression
Homeostasis
Immune system
Kinases
Mammals
Phosphorylation
Studies
Transcription factors
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Description
Summary:In this issue of Immunity, Kerdiles et al. (2010) report that Foxo transcription factors are essential for the development and function of Foxp3-expressing regulatory T (Treg) cells via controlling the expression of genes associated with Treg cell function.
ISSN:1074-7613
1097-4180
DOI:10.1016/j.immuni.2010.12.004