Plasma Levels of Matrix Metalloproteinase-9: A Possible Diagnostic Marker of Successful Endovascular Aneurysm Repair

Abstract Objective The aim of the study was evaluating the diagnostic value of plasma matrix metalloproteinase- (MMP)-2 and -9 and tissue inhibitor of MMP-1 (TIMP-1) for endoleak detection after endovascular aneurysm repair (EVAR). Report Consecutive EVAR patients ( n  = 17) with endoleak and matche...

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Published in:European journal of vascular and endovascular surgery 2012-02, Vol.43 (2), p.171-172
Main Authors: Hellenthal, F.A.M.V.I, Ten Bosch, J.A, Pulinx, B, Wodzig, W.K.W.H, de Haan, M.W, Prins, M.H, Welten, R.J.T.J, Teijink, J.A.W, Schurink, G.W.H
Format: Article
Language:English
Subjects:
Abdominal aortic aneurysm
Aged
Aged, 80 and over
Angiography
Aortic Aneurysm, Abdominal - blood
Aortic Aneurysm, Abdominal - surgery
Biomarkers - blood
Blood Vessel Prosthesis Implantation
Case-Control Studies
Diagnosis
Endoleak
Endoleak - blood
Endoleak - diagnostic imaging
Enzyme-Linked Immunosorbent Assay
Female
Follow-Up Studies
Humans
Male
Matrix Metalloproteinase 2 - blood
Matrix Metalloproteinase 9 - blood
Middle Aged
MMP-9
Prospective Studies
Protease Inhibitors - blood
Regression Analysis
ROC Curve
Sensitivity and Specificity
Surgery
Tissue Inhibitor of Metalloproteinase-1 - blood
Tomography, X-Ray Computed
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Summary:Abstract Objective The aim of the study was evaluating the diagnostic value of plasma matrix metalloproteinase- (MMP)-2 and -9 and tissue inhibitor of MMP-1 (TIMP-1) for endoleak detection after endovascular aneurysm repair (EVAR). Report Consecutive EVAR patients ( n  = 17) with endoleak and matched controls without endoleak ( n  = 20) were prospectively enrolled. Increased levels of MMP-9 were observed in patients with endoleak ( P  
ISSN:1078-5884
1532-2165
DOI:10.1016/j.ejvs.2011.10.014