Value of Carotid Intima-Media Thickness and Significant Carotid Stenosis as Markers of Stroke Recurrence

Data on the predictive value of carotid intima-media thickness (IMT) for stroke recurrence are scarce. We sought to analyze outcome differences in stroke patients with high IMT values compared with patients with significant carotid stenosis (SCS). The multicenter observational ARTICO study included...

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Bibliographic Details
Published in:Stroke (1970) 2011-11, Vol.42 (11), p.3099-3104
Main Authors: ROQUER, Jaume, SEGURA, Tomás, SERENA, Joaquin, CUADRADO-GODIA, Elisa, BLANCO, Miguel, GARCIA-GARCIA, Jorge, CASTILLO, Jose
Format: Article
Language:English
Subjects:
Aged
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Carotid Intima-Media Thickness - standards
Carotid Stenosis - diagnostic imaging
Cohort Studies
Female
Follow-Up Studies
Humans
Male
Medical sciences
Middle Aged
Neurology
Predictive Value of Tests
Secondary Prevention
Stroke - diagnostic imaging
Stroke - prevention & control
Vascular diseases and vascular malformations of the nervous system
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Summary:Data on the predictive value of carotid intima-media thickness (IMT) for stroke recurrence are scarce. We sought to analyze outcome differences in stroke patients with high IMT values compared with patients with significant carotid stenosis (SCS). The multicenter observational ARTICO study included 620 independent patients older than 60 years with a first-ever noncardioembolic stroke. Patients were followed-up for 1 year. The primary end point was a composite of cardiovascular events and death. The IMT-ARTICO substudy analyzed ultrasonographic data from 599 patients. After Doppler carotid echography, patients were classified into the SCS group (carotid stenosis ≥50%; 117 cases), high IMT group (patients with the common carotid IMT in the highest quartile ≥1.11 mm and without SCS; 110 cases), and control group (stroke patients with an IMT
ISSN:0039-2499
1524-4628
DOI:10.1161/strokeaha.110.612010