Effect of two routes of administration of dexamethasone on pain, edema, and trismus in impacted lower third molar surgery

Purpose The aim of the present study was to compare pain, edema, and trismus in the postoperative period following third molar surgery using 8 mg of dexamethasone administered either orally or through local injection. Methods A prospective, controlled, randomized trial was carried out involving 60 l...

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Bibliographic Details
Published in:Oral and maxillofacial surgery 2011-12, Vol.15 (4), p.217-223
Main Authors: Antunes, Antonio Azoubel, Avelar, Rafael Linard, Martins Neto, Evandro Carneiro, Frota, Riedel, Dias, Emanuel
Format: Article
Language:English
Subjects:
Administration, Oral
Adolescent
Adult
Analysis of Variance
Dentistry
Dexamethasone - administration & dosage
Edema - etiology
Edema - prevention & control
Facial Pain - etiology
Facial Pain - prevention & control
Glucocorticoids - administration & dosage
Humans
Injections, Intramuscular
Mandible
Medicine
Medicine & Public Health
Molar, Third - surgery
Oral and Maxillofacial Surgery
Original Article
Pain, Postoperative - etiology
Pain, Postoperative - prevention & control
Premedication
Prospective Studies
Tooth Extraction - adverse effects
Tooth, Impacted - surgery
Trismus - etiology
Trismus - prevention & control
Young Adult
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Summary:Purpose The aim of the present study was to compare pain, edema, and trismus in the postoperative period following third molar surgery using 8 mg of dexamethasone administered either orally or through local injection. Methods A prospective, controlled, randomized trial was carried out involving 60 lower third molar surgeries in 67 patients between October 2008 and June 2009. The sample was randomly divided into three groups: group A (local injection), group B (tablets), and group C (control). In all cases, either ostectomy or crown sectioning was employed. On the second and seventh day following surgery, linear edema was determined using facial landmarks, and maximal mouth opening measurements were performed. Postoperative pain was recorded using a visual analog scale. Results Patient age ranged from 14 to 37 years (mean, 21.0 years). With regard to pain, edema, and trismus, the two administration routes tested (local injection and tablets) demonstrated similar efficacy, and both methods achieved better results in comparison to the control group. Conclusion Both the oral administration and local injection of dexamethasone proved effective in reducing pain, edema, and trismus compared to control group following lower third molar surgeries, achieving similar results.
ISSN:1865-1550
1865-1569
DOI:10.1007/s10006-011-0290-9