Characterization of surgical aerosols by the compact single-particle mass spectrometer LAMPAS 3

A new method is presented using an optical particle counter and the compact mobile laser mass spectrometer LAMPAS 3 for in situ analysis of single particles generated by electrosurgical dissection of biological tissues. The instrumental performance is demonstrated for analysing aerosol particles for...

Full description

Saved in:
Bibliographic Details
Published in:Analytical and bioanalytical chemistry 2011-12, Vol.401 (10), p.3165-3172
Main Authors: Hinz, K.-P., Gelhausen, E., Schäfer, K.-C., Takats, Z., Spengler, B.
Format: Article
Language:English
Subjects:
Aerosols
Aerosols - analysis
Analytical Chemistry
Animals
Biochemistry
Cattle
Characterization and Evaluation of Materials
Chemical analysis
Chemistry
Chemistry and Materials Science
Dissection
Evaporation
Food Science
Kidney - chemistry
Laboratory Medicine
Lasers
Liver - chemistry
Mass spectrometers
Mass Spectrometry - instrumentation
Mass Spectrometry - methods
Mathematical analysis
Monitoring/Environmental Analysis
On-line systems
Original Paper
Swine
Volatilization
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new method is presented using an optical particle counter and the compact mobile laser mass spectrometer LAMPAS 3 for in situ analysis of single particles generated by electrosurgical dissection of biological tissues. The instrumental performance is demonstrated for analysing aerosol particles formed during rapid thermal evaporation of porcine liver and porcine kidney tissues. Particle number concentrations of up to 5,000 particles per cubic centimetre were detected during surgical dissection. Chemical analysis of tissue particles was performed by bipolar time-of-flight mass spectrometry. The application of an online mass spectrometric particle analysis for surgical aerosols is reported here for the first time.
ISSN:1618-2642
1618-2650
DOI:10.1007/s00216-011-5465-6