The design of DNA self-assembled computing circuitry

We present a design methodology for a nanoscale self-assembling fabrication process that uses the specificity of DNA hybridization to guide the formation of electrical circuitry. Custom design software allows us to specify the function of a structure in a way similar to that used by VLSI circuit des...

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Published in:IEEE transactions on very large scale integration (VLSI) systems 2004-11, Vol.12 (11), p.1214-1220
Main Authors: Dwyer, C., Vicci, L., Poulton, J., Erie, D., Superfine, R., Washburn, S., Taylor, R.M.
Format: Article
Language:English
Subjects:
Assembly
Associative memories
Circuits
Computer architecture
DNA computing
DNA self-assembly
Metallization
nanoelectronics
Nanowires
Parallel processing
Self-assembly
Sequences
Space technology
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creator Dwyer, C.
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description We present a design methodology for a nanoscale self-assembling fabrication process that uses the specificity of DNA hybridization to guide the formation of electrical circuitry. Custom design software allows us to specify the function of a structure in a way similar to that used by VLSI circuit designers. In an analogous manner to generating masks for a photolithographic process, our software generates an assembly procedure including DNA sequence allocation. We have found that the number of unique DNA sequences needed to assemble a structure scales with its surface area. Using a simple face-serial assembly order we can specify an unambiguous assembly sequence for a structure of any size with only 15 unique DNA sequences.
doi_str_mv 10.1109/TVLSI.2004.836322
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source IEEE Electronic Library (IEL) Journals
subjects Assembly
Associative memories
Circuits
Computer architecture
DNA computing
DNA self-assembly
Metallization
nanoelectronics
Nanowires
Parallel processing
Self-assembly
Sequences
Space technology
title The design of DNA self-assembled computing circuitry
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