The design of DNA self-assembled computing circuitry

We present a design methodology for a nanoscale self-assembling fabrication process that uses the specificity of DNA hybridization to guide the formation of electrical circuitry. Custom design software allows us to specify the function of a structure in a way similar to that used by VLSI circuit des...

Full description

Saved in:
Bibliographic Details
Published in:IEEE transactions on very large scale integration (VLSI) systems 2004-11, Vol.12 (11), p.1214-1220
Main Authors: Dwyer, C., Vicci, L., Poulton, J., Erie, D., Superfine, R., Washburn, S., Taylor, R.M.
Format: Article
Language:English
Subjects:
Assembly
Associative memories
Circuits
Computer architecture
DNA computing
DNA self-assembly
Metallization
nanoelectronics
Nanowires
Parallel processing
Self-assembly
Sequences
Space technology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We present a design methodology for a nanoscale self-assembling fabrication process that uses the specificity of DNA hybridization to guide the formation of electrical circuitry. Custom design software allows us to specify the function of a structure in a way similar to that used by VLSI circuit designers. In an analogous manner to generating masks for a photolithographic process, our software generates an assembly procedure including DNA sequence allocation. We have found that the number of unique DNA sequences needed to assemble a structure scales with its surface area. Using a simple face-serial assembly order we can specify an unambiguous assembly sequence for a structure of any size with only 15 unique DNA sequences.
ISSN:1063-8210
1557-9999
DOI:10.1109/TVLSI.2004.836322